Artificial antibody demonstrates Omicron detection together with all different variants of concern

Bedford, UK | thirteenth January 2022 MIP Diagnostics Ltd. has right this moment introduced that its artificial SARS-CoV-2 antibody (COVID-19 nanoMIPTM) can detect the Omicron variant in addition to beforehand confirmed Alpha, Beta, Delta and Gamma variants of the COVID-19 virus.

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MIP Diagnostics, the main producer of molecularly imprinted polymers (MIPs) –  generally termed artificial antibodies –  has demonstrated that its COVID-19 nanoMIPTM can detect the more and more dominant Omicron variant. The artificial antibody has already been proven to detect the opposite variants of concern – Alpha, Beta, Delta and Gamma.

Preliminary evaluation utilizing pharmaceutical grade molecular modelling software program demonstrated the COVID-19 nanoMIPTM ought to be capable to detect the Omicron variant, and this has now been confirmed by way of laboratory testing. The COVID-19 nanoMIPTM was proven to detect the SARS-CoV-2 Omicron variant spike protein (Native Antigen Firm) in buffer utilizing floor plasmon resonance (SPR), with a magnitude of particular response akin to different variants of the virus beforehand examined. Third occasion validation in a separate sensor gadget might be carried out shortly.  

Initially developed in beneath 8 weeks, the MIP Diagnostics COVID-19 nanoMIPTM gives IVD producers a number of advantages together with excessive selectivity and sensitivity demonstrated to the picogram degree in a variety of COVID-19 sensor gadgets. The sturdy nature of MIPs, when in comparison with antibodies, may even present the superior shelf life and storage properties required by the IVD market as self-testing turns into extra prevalent throughout a number of illness states following the COVID-19 pandemic.

Talking on the brand new information, Alan Thomson, CTO at MIP Diagnostics stated,

In pandemic conditions, a quick response is crucial, and our superior molecular modeling software program had already been utilised to evaluate the efficiency of the COVID-19 nanoMIP towards the Omicron variant in-silico. This new information has confirmed our preliminary findings, and never solely demonstrates the capabilities of the COVID-19 nanoMIP, but in addition helps the broader progress towards sturdy, non-animal derived reagents within the IVD trade.”

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