Hamilton Firm and Rhinostics, an early-stage Harvard College spin-out firm, are combining their respective strengths to enhance the pace and high quality of nasal and nasopharyngeal pattern workflows from assortment to processing whereas additionally decreasing the necessity for energetic labor involvement. This pattern kind is extensively used to detect antibodies and antigens in relation to the novel coronavirus, SARS-CoV-2, and plenty of different pathogens.
The hands-free automated workflow contains use of the RHINOstic™ nasal swab assortment gadget and one in every of Hamilton’s Microlab® STAR™, Microlab NIMBUS®, or Microlab Prep™ automated liquid dealing with workstations, together with the LabElite® DeCapper from Hamilton Storage Applied sciences. This mix of applied sciences alleviates frequent time-consuming bottlenecks in testing workflows, even throughout instances of surging pattern inflow. By growing pattern throughput and decreasing turnaround instances, stakeholders are empowered and knowledgeable to make assured downstream choices concerning affected person therapy methods.
The patent-pending RHINOstic nasal and buccal swab assortment gadget consists of a polypropylene swab stick, built-in into an automation-friendly cap, and a transport tube labeled with a 2-dimensional (2D) barcode. On the level of assortment, the swab minimizes affected person discomfort when gathering pattern. Samples collected by way of the RHINOstic could also be shipped with out use of viral transport media (VTM) to scale back reagent prices and dangers of leaking or aerosol creation. Lack of VTM additionally eliminates the necessity to focus samples previous to evaluation.
As much as 96 samples could also be routinely accessioned and decapped directly utilizing the LabElite DeCapper with a 12-channel head and conversion package. The LabElite DeCapper could also be used as a standalone gadget or built-in with Hamilton’s automated liquid handlers.
Hamilton’s automated liquid handlers constantly and routinely carry out tedious and time-consuming pipetting and different duties in order that customers might attend to increased worth duties. By decreasing energetic labor time, effectivity and productiveness are elevated throughout the laboratory. Walkaway operation additionally reduces the consumer’s threat of biohazard publicity.
Every Hamilton automated liquid handler could also be optimized with instruments and programmed strategies for the appliance at hand, together with PCR, subsequent technology sequencing (NGS), ELISA and extra. Person-friendly software program guides any consumer by way of assay setup and processing, and when used with Hamilton pipette ideas, patented Compressed O-Ring Enlargement (CO-RE®) know-how creates a decent seal between pipetting mandrel and tip to assist extremely correct and constant outcomes.
Automated pattern processing utilizing this hands-free automated workflow from Hamilton and Rhinostics could also be simply scaled at any time with out growing labor, gear or reagent prices.
About Hamilton Robotics
Hamilton Robotics, an affiliate of Hamilton Firm, is a number one world producer offering automated liquid dealing with workstations and laboratory automation know-how to the scientific group. With a give attention to progressive design, Hamilton merchandise incorporate patented liquid dealing with applied sciences right into a portfolio that features liquid dealing with platforms, normal application-based options, small units, consumables, and OEM liquid dealing with options.
Identified for advancing life science, medical diagnostics, forensics and biotechnology industries, Hamilton merchandise provide reliability, efficiency and suppleness. Making certain a steady dedication to high quality, Hamilton makes use of state-of-the-art manufacturing at manufacturing services in Reno, Nevada and Bonaduz, Switzerland, and has earned a world ISO 9001 certification.
Privately held, Hamilton maintains headquarters in Reno, Nevada; Franklin, Massachusetts; and Bonaduz, Switzerland, together with subsidiary places of work all through the world. www.hamiltoncompany.com/robotics
Rhinostics Inc. is an early stage firm commercializing a easy and stylish answer to deliver efficiencies and price financial savings to the laboratory workflow. The RHINOstic nasal swab supplies options that enhance pattern throughput by greater than 10-fold whereas eradicating labor and errors from the laboratory workflow. The swab is built-in onto a cap that may be automated for elimination from the tube whereas all 96 samples are concurrently accessioned by way of scanning a 2D barcode on the underside of the tubes.
Moreover, the gadget permits dry cargo of respiratory samples with out viral transport media, and the nasal assortment permits for a simple and cozy assortment. Viral samples may be launched immediately right into a small quantity of saline, offering pattern focus of 30x or better, offering better standardization and bettering downstream assay reliability.
The product supplies a direct influence to growing COVID testing efficiencies whereas being relevant to broader respiratory viral, bacterial, and genetic testing utilizing the polymerase chain response (PCR) and subsequent technology sequencing (NGS).
The RHINOstic product is registered as Class I exempt medical gadget with the FDA and is obtainable for buy. To be taught extra, go to https://www.rhinostics.com.
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