Parietooccipital fissure contributes to the invasion sample of posterior medial temporal gliomas

Researchers from 4 educational neurosurgical facilities in Japan discovered that the parietooccipital fissure, which divides the temporal, occipital, and parietal lobes of the mind, acts as an impediment that will lead to much less invasion of posterior medial temporal gliomas towards the occipital lobe.

Detailed findings, together with photographs obtained with magnetic resonance and diffusion tensor imaging and fiber tractography, are supplied within the article “Function of the parietooccipital fissure and its implications within the pathophysiology of posterior medial temporal gliomas,” by Ichiyo Shibahara, MD, PhD, and colleagues, revealed immediately within the Journal of Neurosurgery (https://thejns.org/doi/10.3171/2021.7.JNS21990).

Gliomas are the most typical major mind tumors and have a poor prognosis even with presently accessible therapies. An essential remedy technique is surgical removing of as a lot tumor as potential with out damaging essential purposeful areas of the mind, a precaution that requires detailed info concerning the person anatomy of every affected person.

On this examine, the authors carried out tumor removing and assessed the anatomical structure between the tumor location and the parietooccipital fissure in 24 sufferers with posterior medial temporal gliomas. In all sufferers, the anterior finish of the parietooccipital fissure was the posterior border of the tumor. Magnetic resonance imaging of 20 sufferers confirmed that the tumor invaded alongside and anterior to the parietooccipital fissure, extending to the isthmus of the cingulate gyrus and the splenium of the corpus callosum. Fiber tracts operating by way of the posterior medial temporal lobe have been noticed to correspond to those invasion patterns. Diffusion tensor imaging and fiber tractography additionally confirmed that fibers operating towards the occipital lobe made a detour to keep away from the parietooccipital fissure. These findings spotlight the significance of the parietooccipital fissure in figuring out the invasion sample of posterior medial temporal gliomas.

Because the researchers state, their proof confirms that in sufferers with posterior medial temporal glioma the parietooccipital fissure is an uninterrupted foremost sulcus comprising the posterior boundary of glioma invasion. Subsequently, this fissure is a key landmark for understanding the advanced anatomical structure and invasion sample of posterior medial temporal gliomas throughout preoperative evaluation, info that will result in simpler surgical remedy.

When requested in regards to the examine, Dr. Shibahara mentioned, “All neurosurgeons/neuro-oncologists share some impression that gliomas invade in a selected route; nevertheless, just a few research have centered on demonstrating such phenomena. On this examine we observed that posterior medial temporal gliomas in several sufferers offered not solely related invasion patterns but in addition radiological options indicating a transparent posterior border. We discovered that invasion of glioma cells was extremely influenced by the parietooccipital fissure, suggesting a generalized sample through which sulci act because the anatomical boundary of glioma invasion.”

Supply:

American Affiliation of Neurological Surgeons (AANS)

Journal reference:

Shibahara, I., et al. (2021) Function of the parietooccipital fissure and its implications within the pathophysiology of posterior medial temporal gliomas. Journal of Neurosurgery. doi.org/10.3171/2021.7.JNS21990.

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