Superior instruments for Glycobiology analysis

Drawing upon over 30-years’ expertise of serving the glycobiology analysis group – AMSBIO has established a complete portfolio of high-quality reagents together with distinctive ranges of antibodies, lectins, enzymes, assay kits and requirements, backed by in-depth technical help.

Hyaluronic Acid staining with HABP (b-VG1 inexperienced) of an expanded cumulus oocyte advanced inside a mouse ovarian follicle; blue is DAPI staining. Picture courtesy of Tony Day, College of Manchester, UK. Picture credit score: AMSBio

Glycobiology (the research of the construction, biosynthesis, and biology of carbohydrates) is a posh and dynamic space of analysis that mixes enzymology, molecular and mobile biology, natural chemistry and supplies science. Extensively acknowledged as important for each mobile biology and research of carbohydrate-based medication and therapeutics, glycobiology is a quickly increasing area of analysis that’s attracting numerous consideration.

Dr William Hadlington-Sales space, Glycobiology product supervisor commented “To keep up our international repute because the premier provider for the glycobiology analysis group, we’re continuously introducing new modern merchandise in addition to investing in stock to assist us provide researchers with key reagents once they want them”.

Working with main analysis teams – AMSBIO has established an unmatched vary of monoclonal antibodies and binding proteins for proteoglycan, glycosaminoglycan (GAG) and ganglioside analysis together with Heparan Sulfate, Chondroitin Sulfate, Keratan Sulfate and Hyaluronic Acid. AMSBIO’s antibodies present excessive ranges of specificity and affinity to focus on antigens; and most glycobiology antibodies work throughout many mannequin species.

AMSBIO additionally presents a complete vary of specialist enzymes for glycobiology analysis and different functions. The corporate’s glycosaminoglycan (GAG) degrading enzymes embrace chondroitinase, heparinase and hyaluronidase enzymes.

The enzymes heparanase and hyaluronidase each play important roles degrading carbohydrates within the extracellular matrix; and chondroitinase ABC has been related to selling neural restore and plasticity. AMSBIO presents kits for measuring exercise of those enzymes in cell tradition supernatants, plasma and different organic fluids, and tissue samples. These kits have been broadly utilized by main analysis teams for research on anti-inflammatory responses, kidney illness, and most cancers as they remedy the standardization and efficiency points related to conventional measurement strategies for a majority of these enzymes.

For additional data on superior instruments for glycobiology analysis please go to  https://www.amsbio.com/research-areas/glycobiology or contact AMSBIO on+44-1235-828200 / +1-617-945-5033 / [email protected].

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